Ferritin: What Your Results Mean
Ferritin is a protein that stores iron inside your cells. A blood test for ferritin tells you how much iron your body has in reserve. Normal range is roughly 30–300 ng/mL for men and 12–150 ng/mL for women. Low ferritin is the earliest and most sensitive sign of iron deficiency — it drops long before hemoglobin does.
What Is Ferritin?
Ferritin acts as your body's iron savings account. While most iron circulates in hemoglobin (carrying oxygen in red blood cells) and some rides on transferrin (the transport protein), ferritin stores the surplus. When your body needs iron — to make new red blood cells, support muscle function, or run hundreds of enzymatic reactions — it draws from these ferritin reserves.
A single ferritin molecule can hold up to 4,500 iron atoms. Your liver, spleen, and bone marrow are the main storage sites. The ferritin level in your blood reflects how full those stores are.
This is why ferritin is often the first test doctors order when investigating fatigue, hair loss, or unexplained anemia. It catches iron depletion at the earliest stage, before it shows up in your CBC.
Reference Ranges
| Classification | Range |
|---|---|
| Severely Low | Below 12 ng/mL |
| Low (Iron Deficiency) | 12 – 29 ng/mL |
| Normal (Women) | 12 – 150 ng/mL |
| Normal (Men) | 30 – 300 ng/mL |
| Elevated | 300 – 500 ng/mL |
| High | Above 500 ng/mL |
Important: Ferritin is also an acute-phase reactant — it rises during inflammation, infection, and liver disease. A "normal" ferritin in someone with active inflammation may actually mask true iron deficiency. If CRP or ESR are elevated, the ferritin cutoff for deficiency should be raised to around 100 ng/mL.
What Causes Low Ferritin?
- Blood loss — heavy periods, GI bleeding (ulcers, polyps, hemorrhoids), frequent blood donation
- Inadequate dietary iron — vegetarian/vegan diets, restrictive eating
- Malabsorption — celiac disease, inflammatory bowel disease, gastric bypass, H. pylori infection
- Increased demand — pregnancy, rapid growth in adolescents, endurance athletes
- Chronic conditions — hypothyroidism can impair iron absorption
Symptoms of low ferritin include fatigue, weakness, hair loss, brittle nails, restless legs, difficulty concentrating, and feeling cold. Many people with ferritin under 30 have symptoms even though their hemoglobin is still "normal."
What Causes High Ferritin?
- Inflammation or infection — the most common cause of elevated ferritin
- Liver disease — hepatitis, fatty liver, cirrhosis release stored ferritin
- Hemochromatosis — genetic iron overload disorder (check transferrin saturation)
- Alcohol use
- Metabolic syndrome and obesity
- Certain cancers — particularly lymphoma and leukemia
Ferritin vs. Other Iron Tests
| Test | What It Measures |
|---|---|
| Ferritin | Iron in storage — earliest to drop in deficiency |
| Serum Iron | Iron circulating in blood right now (fluctuates daily) |
| Transferrin / TIBC | Iron transport capacity — rises when stores are low |
| Transferrin Saturation | % of transport protein loaded with iron |
| Hemoglobin | Iron in red blood cells — last to drop in deficiency |
The classic iron deficiency progression: ferritin drops first → transferrin saturation falls → MCV shrinks (microcytic) → hemoglobin finally drops. By the time you're anemic, iron stores have been empty for a while.
Look Up Your Ferritin Value
Select your result below to see a detailed breakdown:
Frequently Asked Questions
A ferritin below 30 ng/mL is widely considered iron deficient. Many clinicians use 12 ng/mL as the cutoff, but research shows symptoms and impaired function begin well above that. If you have inflammation, a ferritin under 100 ng/mL may indicate true deficiency.
Yes. Ferritin drops long before hemoglobin does. You can have a completely normal CBC with a ferritin of 8. This is called iron depletion without anemia, and it still causes symptoms like fatigue and hair loss.
Iron-rich foods (red meat, liver, spinach, lentils), iron supplements (take with vitamin C, away from coffee/tea), and treating the underlying cause of iron loss. Severely low ferritin may require IV iron infusion. Recheck levels after 3 months of supplementation.